Fuchs' endothelial corneal dystrophy: pathology and treatment outcome
نویسندگان
چکیده
منابع مشابه
Fuchs endothelial corneal dystrophy: current perspectives.
Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in vision loss. Hallmarks of the disease include loss of corneal endothelial cells and formation of excrescences of Descemet's membrane. Later stages involve all layers of the cornea. Impairment of endothelial barrier and pump function and cell death from oxidative and unfolded protein stress ...
متن کاملSLC4A11 mutations in Fuchs endothelial corneal dystrophy.
The endothelial (posterior) corneal dystrophies, which result from primary endothelial dysfunction, include Fuchs endothelial corneal dystrophy (FECD), posterior polymorphous corneal dystrophy (PPCD) and congenital hereditary endothelial dystrophy (CHED). Mutations in SLC4A11 gene have been recently identified in patients with recessive CHED (CHED2). In this study, we show that heterozygous mut...
متن کاملCorneal Hydration Control in Fuchs' Endothelial Corneal Dystrophy
Purpose To assess corneal hydration control across a range of severity of Fuchs' endothelial corneal dystrophy (FECD) by measuring the percent recovery per hour (PRPH) of central corneal thickness after swelling the cornea and to determine its association with corneal morphologic parameters. Methods Twenty-three corneas of 23 phakic FECD patients and 8 corneas of 8 healthy control participant...
متن کاملFuchs' Endothelial and Myotonic Dystrophies: Corneal Dystrophy in Myotonic Patients.
We read with great interest the article by Mootha et al. concerning a possible correlation between Fuchs’ endothelial corneal dystrophy (FECD) and myotonic dystrophy (MD). We thank the authors because, among the studies we made trying to understand the reason of low intraocular pressure in patients with MD, they cited one study we published in 2010 where we examined the endothelial cells charac...
متن کاملHearing disability in patients with Fuchs’ endothelial corneal dystrophy: unrecognized co-pathology?
PURPOSE To investigate a possible association between Fuchs' endothelial corneal dystrophy (FECD) and hearing disability. METHODS A cross-sectional observational study was performed at the University Medical Center Utrecht. Cases and controls were patients who were treated by a cornea specialist between 2004 and 2008. FECD patients had either already undergone or were planned for a keratoplas...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2016
ISSN: 1755-375X
DOI: 10.1111/aos.13311